Major Diseases and Medicines in Biology

Diseases

1. 16Cement Disease – Cytosillicosis.
2. Hg – Minamata
3. Phosphorous – Phossy Jaws
4. Textile work us – Byssinosis
5. PCB՚s workers – Yusho disease (Japan – 1968) – Swollen eyelids
6. Espundia – Leishmania braziliensis – Mucus membrane
7. Absence of single Lysosomal hydrolase – Hurler՚s disease
8. Mononucleosis – Epstein Barr virus
9. Blans – Farism – Premature RBS die (so no malaria)
10. Ouch- Ouch/Itai - Itai – Cadmium (Japan) – of bone, liver & Lungs
11. Excess F ⇾ Knock Knee disease or Skeletal fluorosis – Hardened joint
12. Al – Alzheimer՚s disease (Al Deposition in brain)
13. Gas bubble disease of fish – thermal pollution
14. Cotton Dust – Pneumoconiosis – lung fibrosis – Byssinosis
15. Aropecia – Efficiency of Vitamin B7 – Diencephalon
16. Pompe disease – by the buildup of a complex sugar known glycogen in the body՚s cells The accumulation of glycogen in certain organs and tissues, especially muscles, impair their ability to function normally.
17. Asbestos - asbestosis, lung cancer, mesothelioma
18. Deficiency of vitamin E in poultry – Encephalomalacia
19. Inositol – ‘Spectacle eye’ Condition in rat – Alopecia

Name of Organ & Infection

S. No	Organ	Infection
1)	eye	Trachoma
2)	Stomach	Cholera
3)	Brain	Rabies
4)	Pancreas	Diabetes
5)	Intestine	Typhoid
6)	Throat	Diphtheria

Genetic Disorder Disease

1. Down՚s syndrome – 21 trisomy - mental retardation, short body, swelling of tongue,
   folds of eye
2. Patan syndrome – 13 trisomy – infants are deaf, survrive less than 6 months.
3. Edward syndrome – 18 trisomy – infant՚s smaller, elongated skill, malformed ear, receding chin, dislocated hips.

Medicines

s. no.	Medicines	Disease
1)	6MP – mercaplopurine	leukemia
2)	Angina pectoris	nitroglycerin
3)	PAS – p-amino salicylicacid	TB
4)	Atoxyl – soda salt of arsanilic acid	sleeping sickness
5)	Levopoda , 3 (3,4 -dihydroxyphenyl), L-alanine	Parkinsonism
6)	PGF22	Uterine Contractions
7)	Aderaline – act on α1 α2 β1 β2 (not β3)
8)	Non aderaline – act on α1 α2 β1 β2 (not β3)
9)	Anti choline esterase	myasthenia gravis
10)	Choline esterase reactivator – paralidomine – organophosphate
11)	Mycoplasama – resistant to penicillin
12)	resistant to tetracycline	Virus
13)	Zydowoden + AZT	AIDS
14)	sensitive to chloramphenicol, streptomycin.	Protein synthesis of bacteria & mitochondria
15)	Cytoplasmic protein synthesis is sensitive Cycloheximide
16)	2-phenyl ethane	hypnotic
17)	Cytosine arabinoside	anticancer
18)	Ademine arabinoside	antiviral
19)	Bayer	7602 for chagas disease
20)	Benzene & penicillin	Syphilis
21)	Benzyl benzoate	scabies
22)	Vincristine	Ovarian cancers
23)	Geramycin	E. gingivalis
24)	aeranil, antigen, yomesen, ccl4, Nexylroesorcinal	Tenia solium
25)	Hagyl, metrogyl, emetin, arsenic	Amoebic dysentery
26)	Bayer 205, pentamidine, lomidine, melarwopol	Sleeping sickness
27)	antimony, gluconate	Kala azar