Mr. Shubham Dutta (lead author), currently working as a PhD Research Scholar under the guidance of Prof. Akhila K. Sahoo in the School of Chemistry, University of Hyderabad (UoH) along with Shashank, Manash, Shengwen, and Vincent (collaborator on theoretical study from CNRS UMR 8182, Université Paris-Saclay, Orsay Cedex, France) have recently published a work on “Cationic-palladium catalyzed regio- and stereoselective syn-1,2-dicarbofunctionalization of unsymmetrical internal alkynes” in the prestigious journal Nature Communications.
Mr. Shubham Dutta
This discovery paves the way for the step-efficient synthesis of various anti-cancer drugs such as Tamoxifen analogues, which are likely to be more efficient and less damaging to the body. The transformation is highly regioselective and will lead to all-carbon-substituted olefins, structurally similar to Tamoxifen.
Prof. Akhila K. Sahoo
The research paper can be accessed at
https://www.nature.com/articles/s41467-022-28949-7
About University of Hyderabad
The University of Hyderabad is an institute of post-graduate teaching and research. The school was established by an act of the Parliament of India in 1974 as a Central University. Over the years, it has emerged as a top ranking institute of higher education and research in India. The university also offers courses under distance learning programs. The university is a member of the ‘Association of Indian Universities’ (AIU), the ‘Association of Commonwealth Universities’ (ACU) and ‘International Council for Distance Education’. An Academic Staff College has been functioning on the university campus since 1988 under the UGC scheme for improving the standards of teaching in colleges and universities. The college organizes orientation and refresher courses for college and university teachers.
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